GA NCORP

NCORP Trials

Abemaciclib and Letrozole to Treat Endometrial Cancer

Status
Closed
Cancer Type
Unknown Primary
Uterine Cancer
Trial Phase
Phase II
Eligibility
18 Years and older, Female
Study Type
Treatment
NCD ID
NCT04393285
Protocol IDs
GOG-3039 (primary)
NCI-2020-08167
Study Sponsor
Gynecologic Oncology Group

Summary

This is a phase II single arm trial to determine the percentage of patients without evidence
of disease progression on abemaciclib and letrozole in advanced stage, persistent or
recurrent endometrioid endometrial cancer at 6 months. Treatment will continue until either
unacceptable toxicity, progression of disease, or investigator/patient request for
withdrawal.