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Biospecimen Collection in Identifying Genetic Changes in Patients with Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery

Status
Temporarily Closed
Cancer Type
Breast Cancer
Colon/Rectal Cancer
Kidney Cancer
Liver Cancer / Hepatoblastoma
Multiple Myeloma
Plasma cell neoplasm
Prostate Cancer
Solid Tumor
Unknown Primary
Trial Phase
Eligibility
18 Years and older, Male and Female
Study Type
Other
NCD ID
NCT04955808
Protocol IDs
DCP-002 (primary)
DCP-002
DCP-002
NCI-2017-01572
Study Sponsor
National Cancer Institute Division of Cancer Prevention
NCI Full Details
http://clinicaltrials.gov/show/NCT04955808

Summary

This research trial studies how well biospecimen collection works in identifying genetic changes in patients with breast, prostate, colorectal, liver, or kidney cancer or multiple myeloma undergoing surgery. Studying samples collected during surgery may add to the understanding of cancer by looking for the genetic changes that cause early cancer onset in people of certain racial and ethnic groups.

Objectives

PRIMARY OBJECTIVE:
I. To acquire tissue and blood, and other biospecimens for research purposes during procedures for clinical care to accelerate our understanding of the molecular basis of early onset cancers occurring in racial and/or ethnic minority populations through the application of genome analysis technologies, including large- scale genome sequencing and clinical data analysis.

OUTLINE:
Patients undergo collection of tumor tissue during surgery. Patients also undergo blood samples. Samples collected may undergo genetic analysis including whole exome sequencing.

After completion of study, patients are followed for up at 6 and 12 months.
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